Engram Cell Excitability State Determines the Efficacy of Memory Retrieval
نویسندگان
چکیده
منابع مشابه
Memory engram storage and retrieval
A great deal of experimental investment is directed towards questions regarding the mechanisms of memory storage. Such studies have traditionally been restricted to investigation of the anatomical structures, physiological processes, and molecular pathways necessary for the capacity of memory storage, and have avoided the question of how individual memories are stored in the brain. Memory engra...
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How memories are formed and stored in the brain remains a fascinating question in neuroscience. Here we discuss the memory engram theory, our recent attempt to identify and manipulate memory engram cells in the brain with optogenetics, and how these methods are used to address questions such as how false memory is formed and how the valence of a memory can be changed in the brain.
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ژورنال
عنوان ژورنال: Neuron
سال: 2019
ISSN: 0896-6273
DOI: 10.1016/j.neuron.2018.11.029